Lupane Triterpenoids from Acacia mellifera with Cytotoxic Activity
نویسندگان
چکیده
منابع مشابه
Lupane triterpenoids from Acacia mellifera with cytotoxic activity.
Three new pentacyclic triterpenoids: (20R)-3-oxolupan-30-al (1), (20S)-3-oxolupan-30-al (2) and (20R)-28-hydroxylupen-30-al-3-one (3), along with (20S)-3beta-hydroxylupan-30-al (4), the latter previously described as a constituent of an epimeric mixture, were isolated from Acacia mellifera. In addition, the known metabolites 30-hydroxylup-20-(29)-en-3-one (5), 30-hydroxylup-20-(29)-en-3beta-ol ...
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Two new ursane-type triterpenoids, 3β,19α,23-trihydroxyurs-12-en-24-al-28-oic acid (1) and 3β,19α,24-trihydroxy-23-norurs-12-en-28-oic acid (2), two new pregnane derivatives, 3β,12β-dihydroxy-5α-pregnane-14,16-dien-20-one (9) and 12β-hydroxy-5α-pregnane-14,16-dien-3,20-dione (10), and eight known compounds were isolated from the twigs and leaves of Emmenopterys henryi. The structures of the new...
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Leishmaniasis is a neglected tropical disease (NTDs), endemic in 88 countries, affecting more than 12 million people. The treatment consists in pentavalent antimony compounds, amphotericin B, pentamidine and miltefosine, among others. However, these current drugs are limited due to their toxicity, development of biological resistance, length of treatment and high cost. Thus, it is important to ...
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ژورنال
عنوان ژورنال: Molecules
سال: 2007
ISSN: 1420-3049
DOI: 10.3390/12051035